Stelazine advertisement, 1967. Hospital & Community Psychiatry, Vol. 18, No. 10. Flushed therapy doesn't work If you have a psychotic patient who's not improving, and you think he might be flushing his medication -- or hiding it or even swapping it -- specify 'Stelazine' Concentrate, the dosage form you're sure he'll take. Assure drug therapy with STELAZINE® brand of trifluoperazine CONCENTRATE Before prescribing, the physician should be familiar with the complete prescribing information in SK&F literature or PDR. The following is a brief precautionary statement. Contraindications: Comatose or greatly depressed states due to C.N.S. depressants and in cases of blood dyscrasias, bone marrow depression and liver damage. Precautions: Use with caution in angina patients and in patients with impaired cardiovascular systems. Antiemetic effect may mask signs of overdosage of other drugs or symptoms of other disorders. An additive depressant effect is possible when used with other C.N.S. depressants. Prolonged administration of high doses may result in accumulative effects with severe C.N.S. or vasomotor symptoms. If retinal changes occur, discontinue drug. Use in pregnant patients only when necessary for the patient's welfare. Side Effects: Mild drowsiness, dizziness, mild skin reactions, dry mouth, insomnia, amenorrhea, fatigue, muscular weakness, anorexia, rash, lactation, blurred vision and hypotension.. Extrapyramidal reactions (motor restlessness, dystonias and pseudo-parkinsonism) may occur and, in rare instances, may persist. Blood dyscrasias and cholestatic jaundice have been extremely rare. Available: Tablets, 1 mg., 2 mg., 5 mg., and 10 mg.; Injection, 2 mg./cc.; and Concentrate, 10 mg./cc. For symptoms and treatment of overdosage and side effects reported with phenothiazine derivatives, please refer to complete prescribing information. Smith Kline & French Laboratories   ~   SK&F |