Loxapac loxapine advertisement, |
Canadian Journal of Psychiatry, June 1992.
When aggressive behavior in the elderly is the problem
"Regardless of etiology the physician is often in the position of having to intervene in a potentially dangerous situation. Stabilizing the person's behavior must be the first concern." 1. (Ancill)
Loxapac may be particularly beneficial for elderly patients with aggressive behavior.
* Loxapac controls aggressive behavior in both elderly patients and patients sufferring from acute schizophrenia.
* Loxapac produces significant improvement of psychopathology and social functioning in elderly patients compared to haolperidol. 2. (Petrie)
"When treating these [elderly] patients the physician should choose as specific acting a drug as possible, avoiding those with a wide range of actions and resulting side effects." 1. (Ancill)
* Loxapac has fewer extrapyramidal side-effects than holoperidol. 5. (Paprocki)
* Loxapac also has less sedation, orthostatic hypotension and anticholinergic side-effects than lower potency neuroleptics, chlorpromazine and thioridazine. 6. (Bernstein)
Dosage Flexifility For Elderly Patients * Lower initial doses and more gradual titration are recommended for elderly and debilitated patients.
LOXAPAC loxapine succinate Effective Control of Aggression With Moderate Side-Effects   Suggested initial oral dose=5 mg BID
LEDERLE     Cyanamid Canada Inc. Markham     Loxapac is a Registered Trademark of Cyanamid Canada Inc.
For brief prescribing information see page A45