parkinsonism induced by phenothiazines or rauwolfia compounds Cogentin advertisement, 1960

The Parkinsonian script...
...rigidity, tremors, and contractures -- all respond to the long, cumulative action of Cogentin (a bedtime dose often controls symptoms for 24 hours(1)). Cogentin also exerts a "highly selective action against... fixed facies, dysphonia, dysphagia, faulty posture, muscle cramps and 'freezing' of the legs."(2) Parkinsonism due to tranquilizer therapy "is easily alleviated by Cogentin,"(3) even after other drugs fail.(4)
Dosage: Dosage must be individualized. In arteriosclerotic, idiopathic, or postencephalitic parkinsonism, the usual dosage is 1 to 2 mg. daily, with a range of 0.5 to 6 mg. daily. In parkinsonism induced by phenothiazines or rauwolfia compounds, the recommended dosage is 1 to 4 mg. once or twice a day.
Additional information on Cogentin is available to physicians on request.
Now available: Injenction Cogentin, 1 mg. per cc., ampuls of 2 cc. Also available: Tablets Cogentin (quarterscored), 2 mg., bottles of 100 and 1000.
References: 1. A.M.A. Council on Drugs: New and Non-official Drugs 1959, Philadelphia, J.B. Libbincott Company, 1959, p. 252. 2. Doshay, L.J.: J.A.M.A. 162:1031, 1955. 3. Ayd, F.J.: clin. Med. 6:387, 1959. 4. May, R.H.: Am.J.Psychiat. 116:360, 1959.
Cogentin is a trademark of Merck & Co., Inc.
Division of Merck & Co., Inc. Philadelphia 1, Pa.
Methanesulfonate (Benztropine Methanesulfonate)

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