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Artane advertisement, 1968. Hospital & Community Psychiatry, Vol. 19, No. 6. Akathisia. His world is jittery enough without it. Life has been pretty tough, even with the help of tranquilizers. But they're making him shift his legs constantly. And twist his fingers. And smack his tongue. With ARTANE® Trihexyphenidyl HCl he can have his tranquilizers and his composure, too. It could keep his world from closing in. ARTANE -- Fundamental in the total management of Parkinson's disease. Precautions -- Patients with cardiac, liver or kidney disorders or with hypertension should be maintained under close observation. Use with caution in patients with glaucoma, obstructive disease of the gastrointestinal or genitourinary tracts and in elderly males with possible prostatic hypertrophy. Geriatric patients require strict dosage regulation. Incipient glaucoma may be precipitated. Side Effects -- Such effects as dryness of mouth, blurring of vision, dizziness, nausea or nervousness will be experienced by 30 to 50 per cent of patients. Isolated instances of suppurative parotitis, skin rashes, dilatation of the colon, paralytic ileus, delusions, hallucinations and paranoia have been reported. Patients with arteriosclerosis or with a history of idiosyncrasy to drugs may exhibit mental confusion, agitation, disturbed behavior, or nausea and vomiting. Psychiatric disturbances can result from overdosage to sustain euphoria. Side effects of any atropine-like drugs include constipation, drowsiness, urinary hesitancy or retention, tachycardia, dilatation of the pupil, increased intraocular tension, weakness, vomiting and headache. Lederle Laboratories, A Division of American Cyanamid Company, Pearl River, New York Artane® Sequels® Trihexyphenidyl HCl Sustained Release Capsules |