Akineton advertisement, 1960|
Mental Hospitals, Vol. 11, No. 7.
DRUG-INDUCED PARKINSONISM IS ON THE RISE
reflecting the growing use of potent tranquilizers. These extrapyramidal disturbances may be reduced by
lowering tranquilizer dosage.
* "It is almost always preferable, however, to merely add oral Akineton® ...since this avoids the risk of
loss of therapeutic benefit and permits uninterrupted phenothiazine therapy."
AKINETON® brand of biperiden
a prompt, specific countermeasure to drug-induced akinesia
motor restlessness ~ akathisia ~ torticollis ~ oculogyric crises ~ chorea
remarkably safe -- "Akineton was not responsible for a single dangerous or toxic effect in the 500 patients treated."*
Dosage: Doses required to achieve the therapeutic goal are variable and individually adjusted.
The following are average doses.
Drug-induced extrapyramidal disorders ~ 1 tablet (2 mg.) one to three times daily
Parkinson's disease ~ 1 tablet (2 mg.) three or four timese daily
Akineton hydrochloride tablets -- 2 mg., bisected, bottles of 100 and 1000.
*Ayd, Frank J., Jr.: Drug-induced Extrapyramidal Reactions: Their Clinical Manifestations and Treatment with
Akineton. Psychosomatics 1:143 (May-June) 1960.
Knoll Pharmaceutical Company, Orange, New Jersey