when a tranquilized patient gets drug-induced parkinsonism, just add akineton
Akineton advertisement, 1966.
Hospital & Community Psychiatry, Vol. 17, No. 1.

when a tranquilized patient ~ gets drug-induced parkinsonism ~ don't stop tranquilizers ~ just add AKINETON
Akineton relieved parkinson symptoms induced by high phenothiazine administration in all 49 patients studied; the majority of patients remained symptom-free at the low dosage of one half tablet twice daily.(1)
The smaller Akineton dosages may result in fewer side effects and less cost than other adjunctive drugs.(2)
Extrapyramidal reactions, a frequent concomitant of psychotherapeutic drug treatment, can sometimes be controlled by reducing tranquilizer dosage.
But the addition of Akineton usually permits continuation of needed tranquilizers.
So if drug-induced parkinsonism threatens to interrupt tranquilizer therapy in your patients, add Akineton.
Side effects: Minimal (primarily dry mouth and blurred vision). With parenteral administration, short periods of euphoria or disorientation may be noticed in some patients. Transient mild postural hypotension may occur. Caution should be observed in patients with manifest glaucoma. Available as tablets -- 2 mg., bisected, Akineton HCl, and ampules 1 cc. containing 5 mg. Akineton lactate in an aqueous 1.4% sodium lactate solution. See PDR for dosage.
1. Lapolla, A., and Nash, L.R.: Current Therapeutic Research 7:536 (Sept.) 1965. 2. Misevic, G., Janevicius, V., and Csalany, L.: Mental Hospitals 15:212 (Apr.) 1964.
AKINETON® (biperiden)     Knoll Pharmaceutical Company     Orange, New Jersey

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