Butisol advertisement, 1964.|
JAMA: the Journal of the American Medical Association, Vol. 188, No. 7.
When nervous tension augments family problems BUTISOL SODIUM butabarbital sodium restores composure without loss of responsibility
To help the high-strung, tense patient cope with her problems, Butisol Sodium butabarbital sodium can be used to restore calm without appreciable daytime drowsiness or impairment of mental processes.
In a "clinical re-evaluation" of daytime sedatives, Butisol Sodium butabarbital sodium provided the highest rating (therapeutic index).* Unlike phenobarbital, it does not tend to produce cumulative toxicity.
Cautions and Side Effects: At daytime sedative dosage levels, drowsiness, skin rash, "hangover" and systemic disturbances are seldom seen. To be used with caution in moderate to severe hepatic disease. If a hypersensitivity reaction should occur, discontinue use. (Warning: May be habit forming.)
*Batterman, R. C., Grossman, A. J., Leifer, P., and Mouratoff, G. J.: Clinical Re-evaluation of Daytime Sedatives, Postgrad. Med. 26:502-509 (October) 1959.
McNEIL LABORATORIES, INC., Fort Washington, Pa.