in mild depression or in clinical exhaustion syndromes
Ritalin advertisement, 1963.
Mental Hospitals, Vol. 14, No. 2.

Tired patients respond to Ritalin
When lethargy is part of the emotional problem, consider Ritalin. Its gentle stimulant action restores physical and mental activity to normal.
"In mild depression or in clinical exhaustion syndromes, a marginal sympathomimetic drug, like methylphenidate [Ritalin], seems to be the drug of choice
for initiating therapy. It does not have the toxic effects found with the amphetamines or with the hydrazines or other antidepressants."(1)
Other comments on safety of Ritalin: "At no time was there evidence of serious toxic reactions [in a study of 185 patients]. The drug [Ritalin] did not produce
alteration in blood forming factors, kidney and liver function.(2)
"No significant toxic effects have resulted after the continuous administration of [Ritalin] for more than 3 years."(3)
SUPPLIED Tablets, 5 mg. (pale yellow), 10 mg. (pale blue) and 20 mg. (pale orange). For complete information about Ritalin (including dosage, cautions, and
side effects), see current Physicians' Desk Reference or write CIBA, Summit, New Jersey.
1. Siegler, P.F., in Nodine, J.H., and Moyer, J.H. (Editors): Psychsomatic Medicine, The First Hahnemann Symposium, Lea & Febiger, Philadelphia, 1962, p. 582
2. Lapolla, A.: Western Med. 2:383 (Sept.) 1961.
3. Yoss, R.E., and Daly, D.D.: Pediatrics 25:1025 (June) 1960.
RITALIN® hydrochloride (methylphenidate hydrochloride CIBA)         CIBA

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